Biochemical Analysis of Transcriptional Repression byDrosophila Histone Deacetylase 1
نویسندگان
چکیده
منابع مشابه
Myc-mediated transcriptional repression by recruitment of histone deacetylase.
Myc is a transcription factor that features prominently in cancer. The oncogenicity of Myc stems from its ability to regulate expression of genes required for cell growth and proliferation. Although the mechanisms through which Myc activates transcription have been extensively studied, less is known about how Myc represses transcription. Recently, we reported that a conserved element within Myc...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2001
ISSN: 0021-9258
DOI: 10.1074/jbc.c100034200